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#5
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| exactly. the only refractive change that happens to adult hyperopes is that they manifest even more hyperopia over time. kinda shoots the "accommodative stress induces myopia" theory in the foot. never convinced otis though. |
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#4
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| Mike Tyner wrote: - quote - > > I don't know what "stresses" you mean. If "stress" is accommodation,
LarryDoc wrote:then > > there are lots of people who carry around a huge load of habitual > > accommodation and they aren't more prone to nearsightedness. If "stress" is > > something else then please be more specific. - quote - > The uncorrected or undercorrected hyperopes (farsighted) are that group
As usual, I like to cite myself as a wonderful anecdotal example:> of constantly stressed (at least accomodation -wise) people. Despite YEARS of disability due to chronic eye pain, eventually diagnosed (by me) as severe ciliary spasm (call that "accommodative stress?"), eventually diagnosed and "relieved" via MONTHS of nightly cycloplegic use--when the spasm finally "broke," eliciting nearly three diopters of formerly non-existent accommodative amplitudes--it turns out that my underlying cycloplegic refraction HAD NOT CHANGED since I was an infant (I gathered all the records). Still the same high-hyperopic, moderate astigmatic Rx. IF ciliary stress/accommodative tension/call it what you will will elongate the eye .... how come it didn't elongate mine ... after YEARS of EXTREME stress? I was waiting. I would have welcomed it. But it didn't. Outlier or not ... they have to be addressed, no? |
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#3
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| I think for those readers who have not already bought into this, there are two key points to reflect on here: In article <FEv8g.2700$u4.357[at]newsread1.news.pas.earthlink.net> , "Mike Tyner" <mtyner[at]mindspring.com> wrote: - quote - > I don't know what "stresses" you mean. If "stress" is accommodation, then
The uncorrected or undercorrected hyperopes (farsighted) are that group> there are lots of people who carry around a huge load of habitual > accommodation and they aren't more prone to nearsightedness. If "stress" is > something else then please be more specific. of constantly stressed (at least accomodation -wise) people. - quote - > > In Russia, I understand that learning to read is
The other key point. Tested clinically for decades. Wish it worked, but> > delayed from 1-3 years. For this reason and they see less > > nearsightedness accordingly. > We agree that myopia is associated with more time spent reading. Myopia is > an adaptive response to near work. But easing accommodation with special > lenses does not significantly alter that correlation. hope and prayers don't affect change here. - quote - > > This is what I was taught and how I have apporached this problem for
Ah, science.> > over 30 years with my patients. When you are right 9/10 of the time, > > it is hard to chuck it all and start thinking exclusively genetics. > Makes one wonder why the effect doesn't show up in controlled studies. > -MT LB, O.D. |
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#2
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| tkopan1[at]yahoo.com wrote: - quote - > WHile I do not dispute the work of these learned researchers, I have a
your own experience as you relate above for myopia in indian and asian> hard time with the "genetic predisposition" aspect of this. While > certain types of high refractice error of all types has been shown to > be hereditary, vision, being a learned response, changes with the > amount of stress the visual system can handle. > Without trying to be racist or bigoted, we see a alot of high myopia in > the asian populations. These people, as a whole, have different view > of education and instill in their children the need to strive for > excellence. The Indian culture (from India) is much the same way in > the educated segment of their population. populations is actually consistent with the idea of genetic predisposition that you say you have a hard time with. - quote - > Once you use up your ability to absorb visual stress (i.e. reading and
what evidence is there that accommodative spasm/excess leads to axial> CRT use) after doing this task for hours at a time, your ciliary muscle > 'cramps up' causing a blur at far which initially clears, but later can > become permanent by causing elongation of the eyeball which is, by > definition, myopia. elongation? - quote - > This is why so many functionally/developmentally > trained optometrists apply reading lenses to young people. In some > cases, the child's eye is not ready to absorb these kinds of stresses > at such an early age. In Russia, I understand that learning to read is > delayed from 1-3 years. For this reason and they see less > nearsightedness accordingly. > This is what I was taught and how I have apporached this problem for > over 30 years with my patients. When you are right 9/10 of the time, > it is hard to chuck it all and start thinking exclusively genetics. > --Dr. Tom > retinula[at]hotmail.com wrote: > > Hello all, > > here is an interesting and highly speculative article that I was > > alerted to by dr. judy. I believe someone posting here a month or two > > ago gave reference to this theory but a link was never posted. > > > perhaps, after reading this, many of the people who are so frustrated > > about their myopia might consider it in a different light. > > > retinula > > > ============ > > > W. Mak, M.W.M. Kwan, T.S. Cheng, K.H. Chan, R.T.F. Cheung and S.L. Ho > > Department of Medicine, Queen Mary Hospital, University of Hong Kong, > > 4/F, Professorial Block, 102 Pokfulam Road, Hong Kong, PR China > > > Medical Hypotheses 2006 vol. 66(6) Pages 1209-1215 > > > Myopia as a latent phenotype of a pleiotropic gene positively selected > > for facilitating neurocognitive development, and the effects of > > environmental factors in its expression > > > Myopia has become an almost pandemic problem in many populations. > > There are compelling evidence to suggest that myopia is a hereditary > > condition. However, myopia would constitute a definite selection > > disadvantage during most stages of human evolution, which is > > incompatible with its moderate to high prevalence in most modern > > populations. The rapid upsurge of myopia over just a few decades also > > implies that its inheritance does not follow any of the usual > > patterns, and environmental factors may have an important role in > > precipitating its occurrence in those who are genetically predisposed. > > Previous studies showed that myopes were, on average, more intelligent > > than non-myopes, and this association had been attributed to a > > biological link between eye growth and brain development. We propose a > > pleiotropic genetic model to explain the atypical epidemiologic and > > inheritance pattern of myopia and its relationship with neurocognitive > > development. This pleiotropic gene was positively selected for its > > facilitation of human intelligence. The myopic component is a latent > > phenotype; myopia will not be expressed unless some novel external > > factors are encountered (i.e. a "quirk" phenomenon). Therefore, the > > myopic component was selectively neutral in our ancestral environment. > > The net gain in Darwinian fitness enables the pleiotropic gene to > > attain a high frequency in the human population, as reflected by our > > current prevalence of myopia. > > > Shortened Link: > > http://tinyurl.com/kusft |
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#1
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| <tkopan1[at]yahoo.com> wrote - quote - > vision, being a learned response, changes with the
Visual perception simply doesn't vary enough to make your assumption> amount of stress the visual system can handle. possible. Visual perception eg logMAR, color, and stereo acuity are easily measured and they only vary with the obvious interference of drugs, cataracts, refractive error and muscle or receptor fatigue. Those are "stressors" but I gather that isn't the "stress" you mean. I'm not sure what "stress" is, and neither are you. Insofar as vision is the pure neurological function of assimilating sensory input, it's pretty constant after age 8 or so. So is hearing. But axial length is not neurological vision. - quote - > Without trying to be racist or bigoted,
Then it must hold true for a diaspora of Jews, because they're nearsighted,> we see a alot of high myopia in > the asian populations. These people, as a > whole, have different view > of education and instill in their children > the need to strive for > excellence. The Indian culture (from India) > is much the same way in > the educated segment of their population. too. - quote - > Once you use up your ability to absorb
It's a heavily ingrained idea. It just don't work that way.> visual stress (i.e. reading and > CRT use) after doing this task for hours > at a time, your ciliary muscle > 'cramps up' causing a blur at far which > initially clears, but later can > become permanent by causing elongation > of the eyeball which is, by > definition, myopia. - quote - > This is why so many functionally/developmentally
But for the last twenty years, doctors of all flavors have been taught that> trained optometrists apply reading lenses to young people. these techniques were not worthwhile for myopia control, and that those who recommend special glasses for myopia control are bilking the public. You have an uphill climb trying to reverse such conventions. - quote - > In some cases, the child's eye is not ready to
I don't know what "stresses" you mean. If "stress" is accommodation, then> absorb these kinds of stresses > at such an early age. there are lots of people who carry around a huge load of habitual accommodation and they aren't more prone to nearsightedness. If "stress" is something else then please be more specific. - quote - > In Russia, I understand that learning to read is
We agree that myopia is associated with more time spent reading. Myopia is> delayed from 1-3 years. For this reason and they see less > nearsightedness accordingly. an adaptive response to near work. But easing accommodation with special lenses does not significantly alter that correlation. - quote - > This is what I was taught and how I have apporached this problem for
Makes one wonder why the effect doesn't show up in controlled studies.> over 30 years with my patients. When you are right 9/10 of the time, > it is hard to chuck it all and start thinking exclusively genetics. -MT |
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| WHile I do not dispute the work of these learned researchers, I have a hard time with the "genetic predisposition" aspect of this. While certain types of high refractice error of all types has been shown to be hereditary, vision, being a learned response, changes with the amount of stress the visual system can handle. Without trying to be racist or bigoted, we see a alot of high myopia in the asian populations. These people, as a whole, have different view of education and instill in their children the need to strive for excellence. The Indian culture (from India) is much the same way in the educated segment of their population. Once you use up your ability to absorb visual stress (i.e. reading and CRT use) after doing this task for hours at a time, your ciliary muscle 'cramps up' causing a blur at far which initially clears, but later can become permanent by causing elongation of the eyeball which is, by definition, myopia. This is why so many functionally/developmentally trained optometrists apply reading lenses to young people. In some cases, the child's eye is not ready to absorb these kinds of stresses at such an early age. In Russia, I understand that learning to read is delayed from 1-3 years. For this reason and they see less nearsightedness accordingly. This is what I was taught and how I have apporached this problem for over 30 years with my patients. When you are right 9/10 of the time, it is hard to chuck it all and start thinking exclusively genetics. --Dr. Tom retinula[at]hotmail.com wrote: - quote - > Hello all, > here is an interesting and highly speculative article that I was > alerted to by dr. judy. I believe someone posting here a month or two > ago gave reference to this theory but a link was never posted. > perhaps, after reading this, many of the people who are so frustrated > about their myopia might consider it in a different light. > retinula > ============ > W. Mak, M.W.M. Kwan, T.S. Cheng, K.H. Chan, R.T.F. Cheung and S.L. Ho > Department of Medicine, Queen Mary Hospital, University of Hong Kong, > 4/F, Professorial Block, 102 Pokfulam Road, Hong Kong, PR China > Medical Hypotheses 2006 vol. 66(6) Pages 1209-1215 > Myopia as a latent phenotype of a pleiotropic gene positively selected > for facilitating neurocognitive development, and the effects of > environmental factors in its expression > Myopia has become an almost pandemic problem in many populations. > There are compelling evidence to suggest that myopia is a hereditary > condition. However, myopia would constitute a definite selection > disadvantage during most stages of human evolution, which is > incompatible with its moderate to high prevalence in most modern > populations. The rapid upsurge of myopia over just a few decades also > implies that its inheritance does not follow any of the usual > patterns, and environmental factors may have an important role in > precipitating its occurrence in those who are genetically predisposed. > Previous studies showed that myopes were, on average, more intelligent > than non-myopes, and this association had been attributed to a > biological link between eye growth and brain development. We propose a > pleiotropic genetic model to explain the atypical epidemiologic and > inheritance pattern of myopia and its relationship with neurocognitive > development. This pleiotropic gene was positively selected for its > facilitation of human intelligence. The myopic component is a latent > phenotype; myopia will not be expressed unless some novel external > factors are encountered (i.e. a "quirk" phenomenon). Therefore, the > myopic component was selectively neutral in our ancestral environment. > The net gain in Darwinian fitness enables the pleiotropic gene to > attain a high frequency in the human population, as reflected by our > current prevalence of myopia. > Shortened Link: > http://tinyurl.com/kusft |
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#-1
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| Hello all, here is an interesting and highly speculative article that I was alerted to by dr. judy. I believe someone posting here a month or two ago gave reference to this theory but a link was never posted. perhaps, after reading this, many of the people who are so frustrated about their myopia might consider it in a different light. retinula ============ W. Mak, M.W.M. Kwan, T.S. Cheng, K.H. Chan, R.T.F. Cheung and S.L. Ho Department of Medicine, Queen Mary Hospital, University of Hong Kong, 4/F, Professorial Block, 102 Pokfulam Road, Hong Kong, PR China Medical Hypotheses 2006 vol. 66(6) Pages 1209-1215 Myopia as a latent phenotype of a pleiotropic gene positively selected for facilitating neurocognitive development, and the effects of environmental factors in its expression Myopia has become an almost pandemic problem in many populations. There are compelling evidence to suggest that myopia is a hereditary condition. However, myopia would constitute a definite selection disadvantage during most stages of human evolution, which is incompatible with its moderate to high prevalence in most modern populations. The rapid upsurge of myopia over just a few decades also implies that its inheritance does not follow any of the usual patterns, and environmental factors may have an important role in precipitating its occurrence in those who are genetically predisposed. Previous studies showed that myopes were, on average, more intelligent than non-myopes, and this association had been attributed to a biological link between eye growth and brain development. We propose a pleiotropic genetic model to explain the atypical epidemiologic and inheritance pattern of myopia and its relationship with neurocognitive development. This pleiotropic gene was positively selected for its facilitation of human intelligence. The myopic component is a latent phenotype; myopia will not be expressed unless some novel external factors are encountered (i.e. a "quirk" phenomenon). Therefore, the myopic component was selectively neutral in our ancestral environment. The net gain in Darwinian fitness enables the pleiotropic gene to attain a high frequency in the human population, as reflected by our current prevalence of myopia. Shortened Link: http://tinyurl.com/kusft |
| Tags |
| gene, intelligence, myopia, sideeffect |
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