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#72
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| Dr. Leukoma wrote: - quote - > mb wrote:
hmmm.... water and swimming culprits.....> > I added another mother to my support group from Louisana. 16 year old > > boy got the infection in Jan. 2006, a woman from Indiana in January, > > and a man from Kansas city last week. they fought his as herpes for 13 > > months. wonder what kind of solution your patients had used. > I wish I knew. We have traditionally favored Optifree Express over > ReNu because of the broader spectrum of action. > One girl had been hit in the eye with a toy hockey puck from a game. > She mentioned that she had put an ice pack on her eye. She had been > wearing her contact lens at the time. > Another was wearing 30 day continuous wear and had been swimming in > them. > The third was wearing disposable lenses, with no known risk > factors...denied swimming, using tap water, etc. > The fourth was in continuous wear contacts and got dust in her eye out > in west Texas. > All four had atypical presentation, with small dense central > infiltrates under an intact epithelium...too dense in my opinion to be > mistaken for herpes. High magnification revealed faint tracks or > filaments, which are basically tunnels created by the organism. They > all looked septic. > All were positively diagnosed with confocal microscopy. The first > three had similar appearance, which helped with the diagnosis. The > fourth patient was highly atypical in that the infiltrate was small and > peripheral. The department head, who is also an expert on > acanthamoeba, stated that these were the earliest cases he had ever > seen. He later commended me on my early "catch," and for resisting the > urge to reach for the steroids, which causes the organism to spread > quicker. It was not that I was able to correctly diagnose the first > case, but had simply ruled out anything with which I was familiar. I > reasoned first that it was infectious, and secondly that it was > anaerobic. With a medical school nearby, it would have been foolish to > begin treatment without a positive diagnosis. > DrG Your brilliant analysis at the onset saved these patients from further destruction of their eye. If we could clone you excellent doctors, it would be a great benefit to us all. More continuing education in the eye health medical field on this infection is a must. There continues to be a mindset that this infection is so "rare" that doctors are not inclined to even suspect it. That needs to change, but if that won't happen, then prominently displayed warning labels of all water related risks on all contact lens products would reduce this risk as well. Another change on my list is mandatory reporting mechanisms to the CDC on these infections as no one has any clue about increasing or decreasing trends without current or previous statistics. Another stat. that should be in place is lasik gone bad. Thus, my continuing support for passage of the Vision Preservation Act. This legislation is critical...... |
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#71
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| mb wrote: - quote - > I added another mother to my support group from Louisana. 16 year old
I wish I knew. We have traditionally favored Optifree Express over> boy got the infection in Jan. 2006, a woman from Indiana in January, > and a man from Kansas city last week. they fought his as herpes for 13 > months. wonder what kind of solution your patients had used. ReNu because of the broader spectrum of action. One girl had been hit in the eye with a toy hockey puck from a game. She mentioned that she had put an ice pack on her eye. She had been wearing her contact lens at the time. Another was wearing 30 day continuous wear and had been swimming in them. The third was wearing disposable lenses, with no known risk factors...denied swimming, using tap water, etc. The fourth was in continuous wear contacts and got dust in her eye out in west Texas. All four had atypical presentation, with small dense central infiltrates under an intact epithelium...too dense in my opinion to be mistaken for herpes. High magnification revealed faint tracks or filaments, which are basically tunnels created by the organism. They all looked septic. All were positively diagnosed with confocal microscopy. The first three had similar appearance, which helped with the diagnosis. The fourth patient was highly atypical in that the infiltrate was small and peripheral. The department head, who is also an expert on acanthamoeba, stated that these were the earliest cases he had ever seen. He later commended me on my early "catch," and for resisting the urge to reach for the steroids, which causes the organism to spread quicker. It was not that I was able to correctly diagnose the first case, but had simply ruled out anything with which I was familiar. I reasoned first that it was infectious, and secondly that it was anaerobic. With a medical school nearby, it would have been foolish to begin treatment without a positive diagnosis. DrG |
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#70
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| Dr. Leukoma wrote: - quote - > mb wrote:
I added another mother to my support group from Louisana. 16 year old> > Dr. Leukoma wrote: > > > mb wrote: > > > > Dr. Leukoma wrote: > > > > > mb wrote: > > > > > > > > > > > Obviously, since this is such a virulent parasite as we cannot even > > > > > > develop effective antibiotics to kill this parasite, let alone put > > > > > > these cleaning agents in our contact lens solutions, all the more > > > > > > reason for warnings. I am fearful this Acanthamoeba trend will > > > > > > continue and we are entitled to find out why. > > > > > > > > > I guess I need to see some statistics supporting this "trend." Or, is > > > > > it just a "spike" caused by temporary local environmental factors such > > > > > as warmer water, less rainfall causing lakes to be lower, etc. Here at > > > > > the University of Texas Southwestern Medical Center, they are looking > > > > > at the immunological aspects, i.e. what keeps most people from > > > > > contracting the infection. > > > > > > > > > My own pet theory, for which I have no proof whatsoever, is the > > > > > changing perception of the contact lens as a consumer product rather > > > > > than a medical device caused by a number of variables, and increasing > > > > > emphasis on convenience. For some reason, it seems that more people > > > > > consider it their right not to be inconvenienced. The end result? > > > > > Less attention paid to lens hygeine. > > > > > > > > > DrG > > > > > > > We had plenty of doctors very interested in my daughter's case and one > > > > doctor too stated it could possibly be a missing gene in their immune > > > > system that protects others from this parasite. Allergies, possibly, > > > > with medicines that cause the eye to be dryer, don't know. Our tears > > > > do perform a protective barrier against most bacteria. I will email > > > > you the Chicago and Philadelphia studies. The doctors in these two > > > > cities are very concerned about this spike as well. I would like to > > > > know how many cases of Acanthamoeba have occurred in Texas in the last > > > > several years. I have read with interest about Dr. Niederkorn and his > > > > studies on the immunity issue. > > > > > I know Dr. Niederkorn, and we're practically neighbors. > > > > > DrG > > > Small world. Would be interested to get his expert opinion on these > > issues and to ascertain if there are increasing trends in Texas. My > > guess is his expertise in this field already demonstrates there is a > > heightened concern. > I would guess that time frame was atypical, which explains the > interest. As I said earlier, 4 cases in 6 months, without any during > the previous 19 years, and none since. Sounds like an environmental > cause to me. Plus none of the residents got it right. > DrG boy got the infection in Jan. 2006, a woman from Indiana in January, and a man from Kansas city last week. they fought his as herpes for 13 months. wonder what kind of solution your patients had used. |
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#69
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| mb wrote: - quote - > Dr. Leukoma wrote:
I would guess that time frame was atypical, which explains the> > mb wrote: > > > Dr. Leukoma wrote: > > > > mb wrote: > > > > > > > > > Obviously, since this is such a virulent parasite as we cannot even > > > > > develop effective antibiotics to kill this parasite, let alone put > > > > > these cleaning agents in our contact lens solutions, all the more > > > > > reason for warnings. I am fearful this Acanthamoeba trend will > > > > > continue and we are entitled to find out why. > > > > > > > I guess I need to see some statistics supporting this "trend." Or, is > > > > it just a "spike" caused by temporary local environmental factors such > > > > as warmer water, less rainfall causing lakes to be lower, etc. Here at > > > > the University of Texas Southwestern Medical Center, they are looking > > > > at the immunological aspects, i.e. what keeps most people from > > > > contracting the infection. > > > > > > > My own pet theory, for which I have no proof whatsoever, is the > > > > changing perception of the contact lens as a consumer product rather > > > > than a medical device caused by a number of variables, and increasing > > > > emphasis on convenience. For some reason, it seems that more people > > > > consider it their right not to be inconvenienced. The end result? > > > > Less attention paid to lens hygeine. > > > > > > > DrG > > > > > We had plenty of doctors very interested in my daughter's case and one > > > doctor too stated it could possibly be a missing gene in their immune > > > system that protects others from this parasite. Allergies, possibly, > > > with medicines that cause the eye to be dryer, don't know. Our tears > > > do perform a protective barrier against most bacteria. I will email > > > you the Chicago and Philadelphia studies. The doctors in these two > > > cities are very concerned about this spike as well. I would like to > > > know how many cases of Acanthamoeba have occurred in Texas in the last > > > several years. I have read with interest about Dr. Niederkorn and his > > > studies on the immunity issue. > > > I know Dr. Niederkorn, and we're practically neighbors. > > > DrG > Small world. Would be interested to get his expert opinion on these > issues and to ascertain if there are increasing trends in Texas. My > guess is his expertise in this field already demonstrates there is a > heightened concern. interest. As I said earlier, 4 cases in 6 months, without any during the previous 19 years, and none since. Sounds like an environmental cause to me. Plus none of the residents got it right. DrG |
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#68
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| Dr. Leukoma wrote: - quote - > mb wrote:
Small world. Would be interested to get his expert opinion on these> > Dr. Leukoma wrote: > > > mb wrote: > > > > > > > Obviously, since this is such a virulent parasite as we cannot even > > > > develop effective antibiotics to kill this parasite, let alone put > > > > these cleaning agents in our contact lens solutions, all the more > > > > reason for warnings. I am fearful this Acanthamoeba trend will > > > > continue and we are entitled to find out why. > > > > > I guess I need to see some statistics supporting this "trend." Or, is > > > it just a "spike" caused by temporary local environmental factors such > > > as warmer water, less rainfall causing lakes to be lower, etc. Here at > > > the University of Texas Southwestern Medical Center, they are looking > > > at the immunological aspects, i.e. what keeps most people from > > > contracting the infection. > > > > > My own pet theory, for which I have no proof whatsoever, is the > > > changing perception of the contact lens as a consumer product rather > > > than a medical device caused by a number of variables, and increasing > > > emphasis on convenience. For some reason, it seems that more people > > > consider it their right not to be inconvenienced. The end result? > > > Less attention paid to lens hygeine. > > > > > DrG > > > We had plenty of doctors very interested in my daughter's case and one > > doctor too stated it could possibly be a missing gene in their immune > > system that protects others from this parasite. Allergies, possibly, > > with medicines that cause the eye to be dryer, don't know. Our tears > > do perform a protective barrier against most bacteria. I will email > > you the Chicago and Philadelphia studies. The doctors in these two > > cities are very concerned about this spike as well. I would like to > > know how many cases of Acanthamoeba have occurred in Texas in the last > > several years. I have read with interest about Dr. Niederkorn and his > > studies on the immunity issue. > I know Dr. Niederkorn, and we're practically neighbors. > DrG issues and to ascertain if there are increasing trends in Texas. My guess is his expertise in this field already demonstrates there is a heightened concern. |
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#67
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| mb wrote: - quote - > Dr. Leukoma wrote:
I know Dr. Niederkorn, and we're practically neighbors.> > mb wrote: > > > > > Obviously, since this is such a virulent parasite as we cannot even > > > develop effective antibiotics to kill this parasite, let alone put > > > these cleaning agents in our contact lens solutions, all the more > > > reason for warnings. I am fearful this Acanthamoeba trend will > > > continue and we are entitled to find out why. > > > I guess I need to see some statistics supporting this "trend." Or, is > > it just a "spike" caused by temporary local environmental factors such > > as warmer water, less rainfall causing lakes to be lower, etc. Here at > > the University of Texas Southwestern Medical Center, they are looking > > at the immunological aspects, i.e. what keeps most people from > > contracting the infection. > > > My own pet theory, for which I have no proof whatsoever, is the > > changing perception of the contact lens as a consumer product rather > > than a medical device caused by a number of variables, and increasing > > emphasis on convenience. For some reason, it seems that more people > > consider it their right not to be inconvenienced. The end result? > > Less attention paid to lens hygeine. > > > DrG > We had plenty of doctors very interested in my daughter's case and one > doctor too stated it could possibly be a missing gene in their immune > system that protects others from this parasite. Allergies, possibly, > with medicines that cause the eye to be dryer, don't know. Our tears > do perform a protective barrier against most bacteria. I will email > you the Chicago and Philadelphia studies. The doctors in these two > cities are very concerned about this spike as well. I would like to > know how many cases of Acanthamoeba have occurred in Texas in the last > several years. I have read with interest about Dr. Niederkorn and his > studies on the immunity issue. DrG |
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#66
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| Dr. Leukoma wrote: - quote - > mb wrote:
We had plenty of doctors very interested in my daughter's case and one> > > Obviously, since this is such a virulent parasite as we cannot even > > develop effective antibiotics to kill this parasite, let alone put > > these cleaning agents in our contact lens solutions, all the more > > reason for warnings. I am fearful this Acanthamoeba trend will > > continue and we are entitled to find out why. > I guess I need to see some statistics supporting this "trend." Or, is > it just a "spike" caused by temporary local environmental factors such > as warmer water, less rainfall causing lakes to be lower, etc. Here at > the University of Texas Southwestern Medical Center, they are looking > at the immunological aspects, i.e. what keeps most people from > contracting the infection. > My own pet theory, for which I have no proof whatsoever, is the > changing perception of the contact lens as a consumer product rather > than a medical device caused by a number of variables, and increasing > emphasis on convenience. For some reason, it seems that more people > consider it their right not to be inconvenienced. The end result? > Less attention paid to lens hygeine. > DrG doctor too stated it could possibly be a missing gene in their immune system that protects others from this parasite. Allergies, possibly, with medicines that cause the eye to be dryer, don't know. Our tears do perform a protective barrier against most bacteria. I will email you the Chicago and Philadelphia studies. The doctors in these two cities are very concerned about this spike as well. I would like to know how many cases of Acanthamoeba have occurred in Texas in the last several years. I have read with interest about Dr. Niederkorn and his studies on the immunity issue. Absolutely on your pet theory. We have that proof, as the FDA 4 years ago deregulated the plano contact lens as cosmetic, which was sold in dollar stores, because it was a non-prescription lens. It took another two years to get Congress to pass the Plano Contact Lens bill. I emailed 100 senators in July 2005 about this issue and other appalling facts that I discovered. Two days later that legislation was passed in full and now is a law that all contact lenses are medical devices, not to be sold without a prescription. Were they listening to me and my anguished pleas for change? And do you believe there are now states trying to overturn this legislation. Daniel Troy, acting administrator, at that time, saw no problem with deregulating this medical device. And who suffered the consequences - our youth, the ultimate risktakers. It is also an industry marketing their products as quick and convenient. It is a very powerful industry regardless of what good doctors recommend to their patients. |
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#65
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| mb wrote: - quote - > Obviously, since this is such a virulent parasite as we cannot even
I guess I need to see some statistics supporting this "trend." Or, is> develop effective antibiotics to kill this parasite, let alone put > these cleaning agents in our contact lens solutions, all the more > reason for warnings. I am fearful this Acanthamoeba trend will > continue and we are entitled to find out why. it just a "spike" caused by temporary local environmental factors such as warmer water, less rainfall causing lakes to be lower, etc. Here at the University of Texas Southwestern Medical Center, they are looking at the immunological aspects, i.e. what keeps most people from contracting the infection. My own pet theory, for which I have no proof whatsoever, is the changing perception of the contact lens as a consumer product rather than a medical device caused by a number of variables, and increasing emphasis on convenience. For some reason, it seems that more people consider it their right not to be inconvenienced. The end result? Less attention paid to lens hygeine. DrG |
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#64
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| Dr. Leukoma wrote: - quote - > mb wrote:
Yes, I need you experts to keep me in perspective as my passion on this> > Dr. Leukoma wrote: > > > mb wrote: > > > > > > > > > Yes, he is a renowned lasik surgeon. My daughter would let no one > > > > touch her eye except him. His hands are gifted as well as his mind. > > > > We could not have been under better care than that, facing the prospect > > > > that she almost lost her eye battling this infection. > > > > > Interestingly, I know what that is like first hand. One of my most > > > recent patients was damaged by LASIK in 1998, performed by a very > > > gifted surgeon. She hasn't let anyone touch her eyes until now. > > > > > DrG > > > My naivete must be showing. All of us common people put so much trust > > in our doctors when they help us, but even gifted doctors make mistakes > > or procedures just simply go wrong. Yes, lasik can be blindness as > > well as better sight. You are right, of course, no one is protecting > > the consumer on that front either. I am just not surprised anymore. > > Our eyesight has been underprotected for years on all fronts. > > Something needs to change. > > > I hope your gifted hands can restore your patient's sight. > She is quite happy. I just like to keep things in perspective. There > is a jungle of misinformation out there. > By the way, I have been told repeatedly by Alcon that their Optifree > kills acanthamoeba cysts after 6 hours. I know that hydrogen peroxide > kills the cysts as well after a 6 hour soak. This means a 6 hour soak > in the full 3% strength. The unfortunate thing is that the leading > hydrogen peroxide disinfection system begins to neutralize the hydrogen > peroxide as soon as the contact lenses are put into the container. I > am referring of course to the one with the grey disk at the bottom. > It might interest you that at the time of the last "acanthamoeba scare" > almost twenty years ago, there was no effective pharmaceutical agent > against it initially. > DrG issue overcomes me sometimes. And I am glad there are good doctors like you out there who truly care about their patients. We need you and sometimes rely solely on your expertise. Optifree Express is one of the solutions I would feel comfortable using if I wore contacts, and they have validated that for you. Since some solutions cannot even claim acanthamoebicidal, all the more reason for "no swimming" and water related disclosures on all products as that clearly puts you at risk; regardless of how low the risk, there is a risk. Sadly so, yes, you just lost your eye 15-20 years ago. Jackie's doctor was involved in some of the original research during that epidemic that was studied at the CDC while he was a Fellow at Emory University in Atlanta, between 1984-86. He has been clearly aware and has treated these infections for quite a long time. Obviously, since this is such a virulent parasite as we cannot even develop effective antibiotics to kill this parasite, let alone put these cleaning agents in our contact lens solutions, all the more reason for warnings. I am fearful this Acanthamoeba trend will continue and we are entitled to find out why. |
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#63
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| mb wrote: - quote - > Dr. Leukoma wrote:
She is quite happy. I just like to keep things in perspective. There> > mb wrote: > > > > > > Yes, he is a renowned lasik surgeon. My daughter would let no one > > > touch her eye except him. His hands are gifted as well as his mind. > > > We could not have been under better care than that, facing the prospect > > > that she almost lost her eye battling this infection. > > > Interestingly, I know what that is like first hand. One of my most > > recent patients was damaged by LASIK in 1998, performed by a very > > gifted surgeon. She hasn't let anyone touch her eyes until now. > > > DrG > My naivete must be showing. All of us common people put so much trust > in our doctors when they help us, but even gifted doctors make mistakes > or procedures just simply go wrong. Yes, lasik can be blindness as > well as better sight. You are right, of course, no one is protecting > the consumer on that front either. I am just not surprised anymore. > Our eyesight has been underprotected for years on all fronts. > Something needs to change. > I hope your gifted hands can restore your patient's sight. is a jungle of misinformation out there. By the way, I have been told repeatedly by Alcon that their Optifree kills acanthamoeba cysts after 6 hours. I know that hydrogen peroxide kills the cysts as well after a 6 hour soak. This means a 6 hour soak in the full 3% strength. The unfortunate thing is that the leading hydrogen peroxide disinfection system begins to neutralize the hydrogen peroxide as soon as the contact lenses are put into the container. I am referring of course to the one with the grey disk at the bottom. It might interest you that at the time of the last "acanthamoeba scare" almost twenty years ago, there was no effective pharmaceutical agent against it initially. DrG |
| Tags |
| acuvvue, advance, oasys, swimming |
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