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  #72  
Old 06-05-2006, 01:48 PM
mb
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Posts: n/a
Default Re: will acuvvue oasys or advance 2 be okay for swimming?


Dr. Leukoma wrote:
- quote -

> mb wrote:
> > I added another mother to my support group from Louisana. 16 year old
> > boy got the infection in Jan. 2006, a woman from Indiana in January,
> > and a man from Kansas city last week. they fought his as herpes for 13
> > months. wonder what kind of solution your patients had used.
> I wish I knew. We have traditionally favored Optifree Express over
> ReNu because of the broader spectrum of action.
> One girl had been hit in the eye with a toy hockey puck from a game.
> She mentioned that she had put an ice pack on her eye. She had been
> wearing her contact lens at the time.
> Another was wearing 30 day continuous wear and had been swimming in
> them.
> The third was wearing disposable lenses, with no known risk
> factors...denied swimming, using tap water, etc.
> The fourth was in continuous wear contacts and got dust in her eye out
> in west Texas.
> All four had atypical presentation, with small dense central
> infiltrates under an intact epithelium...too dense in my opinion to be
> mistaken for herpes. High magnification revealed faint tracks or
> filaments, which are basically tunnels created by the organism. They
> all looked septic.
> All were positively diagnosed with confocal microscopy. The first
> three had similar appearance, which helped with the diagnosis. The
> fourth patient was highly atypical in that the infiltrate was small and
> peripheral. The department head, who is also an expert on
> acanthamoeba, stated that these were the earliest cases he had ever
> seen. He later commended me on my early "catch," and for resisting the
> urge to reach for the steroids, which causes the organism to spread
> quicker. It was not that I was able to correctly diagnose the first
> case, but had simply ruled out anything with which I was familiar. I
> reasoned first that it was infectious, and secondly that it was
> anaerobic. With a medical school nearby, it would have been foolish to
> begin treatment without a positive diagnosis.
> DrG

hmmm.... water and swimming culprits.....

Your brilliant analysis at the onset saved these patients from further
destruction of their eye. If we could clone you excellent doctors, it
would be a great benefit to us all. More continuing education in the
eye health medical field on this infection is a must. There continues
to be a mindset that this infection is so "rare" that doctors are not
inclined to even suspect it. That needs to change, but if that won't
happen, then prominently displayed warning labels of all water related
risks on all contact lens products would reduce this risk as well.

Another change on my list is mandatory reporting mechanisms to the CDC
on these infections as no one has any clue about increasing or
decreasing trends without current or previous statistics. Another
stat. that should be in place is lasik gone bad. Thus, my continuing
support for passage of the Vision Preservation Act. This legislation
is critical......

Alt 06-05-2006, 01:48 PM
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  #71  
Old 06-05-2006, 12:26 PM
Dr. Leukoma
Guest
 
Posts: n/a
Default Re: will acuvvue oasys or advance 2 be okay for swimming?


mb wrote:

- quote -

> I added another mother to my support group from Louisana. 16 year old
> boy got the infection in Jan. 2006, a woman from Indiana in January,
> and a man from Kansas city last week. they fought his as herpes for 13
> months. wonder what kind of solution your patients had used.

I wish I knew. We have traditionally favored Optifree Express over
ReNu because of the broader spectrum of action.

One girl had been hit in the eye with a toy hockey puck from a game.
She mentioned that she had put an ice pack on her eye. She had been
wearing her contact lens at the time.

Another was wearing 30 day continuous wear and had been swimming in
them.

The third was wearing disposable lenses, with no known risk
factors...denied swimming, using tap water, etc.

The fourth was in continuous wear contacts and got dust in her eye out
in west Texas.

All four had atypical presentation, with small dense central
infiltrates under an intact epithelium...too dense in my opinion to be
mistaken for herpes. High magnification revealed faint tracks or
filaments, which are basically tunnels created by the organism. They
all looked septic.

All were positively diagnosed with confocal microscopy. The first
three had similar appearance, which helped with the diagnosis. The
fourth patient was highly atypical in that the infiltrate was small and
peripheral. The department head, who is also an expert on
acanthamoeba, stated that these were the earliest cases he had ever
seen. He later commended me on my early "catch," and for resisting the
urge to reach for the steroids, which causes the organism to spread
quicker. It was not that I was able to correctly diagnose the first
case, but had simply ruled out anything with which I was familiar. I
reasoned first that it was infectious, and secondly that it was
anaerobic. With a medical school nearby, it would have been foolish to
begin treatment without a positive diagnosis.

DrG

  #70  
Old 06-05-2006, 03:37 AM
mb
Guest
 
Posts: n/a
Default Re: will acuvvue oasys or advance 2 be okay for swimming?


Dr. Leukoma wrote:
- quote -

> mb wrote:
> > Dr. Leukoma wrote:
> > > mb wrote:
> > > > Dr. Leukoma wrote:
> > > > > mb wrote:
> > > > > > > > > > > Obviously, since this is such a virulent parasite as we cannot even
> > > > > > develop effective antibiotics to kill this parasite, let alone put
> > > > > > these cleaning agents in our contact lens solutions, all the more
> > > > > > reason for warnings. I am fearful this Acanthamoeba trend will
> > > > > > continue and we are entitled to find out why.
> > > > > > > > > I guess I need to see some statistics supporting this "trend." Or, is
> > > > > it just a "spike" caused by temporary local environmental factors such
> > > > > as warmer water, less rainfall causing lakes to be lower, etc. Here at
> > > > > the University of Texas Southwestern Medical Center, they are looking
> > > > > at the immunological aspects, i.e. what keeps most people from
> > > > > contracting the infection.
> > > > > > > > > My own pet theory, for which I have no proof whatsoever, is the
> > > > > changing perception of the contact lens as a consumer product rather
> > > > > than a medical device caused by a number of variables, and increasing
> > > > > emphasis on convenience. For some reason, it seems that more people
> > > > > consider it their right not to be inconvenienced. The end result?
> > > > > Less attention paid to lens hygeine.
> > > > > > > > > DrG
> > > > > > > We had plenty of doctors very interested in my daughter's case and one
> > > > doctor too stated it could possibly be a missing gene in their immune
> > > > system that protects others from this parasite. Allergies, possibly,
> > > > with medicines that cause the eye to be dryer, don't know. Our tears
> > > > do perform a protective barrier against most bacteria. I will email
> > > > you the Chicago and Philadelphia studies. The doctors in these two
> > > > cities are very concerned about this spike as well. I would like to
> > > > know how many cases of Acanthamoeba have occurred in Texas in the last
> > > > several years. I have read with interest about Dr. Niederkorn and his
> > > > studies on the immunity issue.
> > > > > I know Dr. Niederkorn, and we're practically neighbors.
> > > > > DrG
> > > Small world. Would be interested to get his expert opinion on these
> > issues and to ascertain if there are increasing trends in Texas. My
> > guess is his expertise in this field already demonstrates there is a
> > heightened concern.
> I would guess that time frame was atypical, which explains the
> interest. As I said earlier, 4 cases in 6 months, without any during
> the previous 19 years, and none since. Sounds like an environmental
> cause to me. Plus none of the residents got it right.
> DrG

I added another mother to my support group from Louisana. 16 year old
boy got the infection in Jan. 2006, a woman from Indiana in January,
and a man from Kansas city last week. they fought his as herpes for 13
months. wonder what kind of solution your patients had used.

  #69  
Old 06-05-2006, 12:33 AM
Dr. Leukoma
Guest
 
Posts: n/a
Default Re: will acuvvue oasys or advance 2 be okay for swimming?


mb wrote:
- quote -

> Dr. Leukoma wrote:
> > mb wrote:
> > > Dr. Leukoma wrote:
> > > > mb wrote:
> > > > > > > > > Obviously, since this is such a virulent parasite as we cannot even
> > > > > develop effective antibiotics to kill this parasite, let alone put
> > > > > these cleaning agents in our contact lens solutions, all the more
> > > > > reason for warnings. I am fearful this Acanthamoeba trend will
> > > > > continue and we are entitled to find out why.
> > > > > > > I guess I need to see some statistics supporting this "trend." Or, is
> > > > it just a "spike" caused by temporary local environmental factors such
> > > > as warmer water, less rainfall causing lakes to be lower, etc. Here at
> > > > the University of Texas Southwestern Medical Center, they are looking
> > > > at the immunological aspects, i.e. what keeps most people from
> > > > contracting the infection.
> > > > > > > My own pet theory, for which I have no proof whatsoever, is the
> > > > changing perception of the contact lens as a consumer product rather
> > > > than a medical device caused by a number of variables, and increasing
> > > > emphasis on convenience. For some reason, it seems that more people
> > > > consider it their right not to be inconvenienced. The end result?
> > > > Less attention paid to lens hygeine.
> > > > > > > DrG
> > > > > We had plenty of doctors very interested in my daughter's case and one
> > > doctor too stated it could possibly be a missing gene in their immune
> > > system that protects others from this parasite. Allergies, possibly,
> > > with medicines that cause the eye to be dryer, don't know. Our tears
> > > do perform a protective barrier against most bacteria. I will email
> > > you the Chicago and Philadelphia studies. The doctors in these two
> > > cities are very concerned about this spike as well. I would like to
> > > know how many cases of Acanthamoeba have occurred in Texas in the last
> > > several years. I have read with interest about Dr. Niederkorn and his
> > > studies on the immunity issue.
> > > I know Dr. Niederkorn, and we're practically neighbors.
> > > DrG
> Small world. Would be interested to get his expert opinion on these
> issues and to ascertain if there are increasing trends in Texas. My
> guess is his expertise in this field already demonstrates there is a
> heightened concern.

I would guess that time frame was atypical, which explains the
interest. As I said earlier, 4 cases in 6 months, without any during
the previous 19 years, and none since. Sounds like an environmental
cause to me. Plus none of the residents got it right.

DrG

  #68  
Old 06-04-2006, 07:10 PM
mb
Guest
 
Posts: n/a
Default Re: will acuvvue oasys or advance 2 be okay for swimming?


Dr. Leukoma wrote:
- quote -

> mb wrote:
> > Dr. Leukoma wrote:
> > > mb wrote:
> > > > > > > Obviously, since this is such a virulent parasite as we cannot even
> > > > develop effective antibiotics to kill this parasite, let alone put
> > > > these cleaning agents in our contact lens solutions, all the more
> > > > reason for warnings. I am fearful this Acanthamoeba trend will
> > > > continue and we are entitled to find out why.
> > > > > I guess I need to see some statistics supporting this "trend." Or, is
> > > it just a "spike" caused by temporary local environmental factors such
> > > as warmer water, less rainfall causing lakes to be lower, etc. Here at
> > > the University of Texas Southwestern Medical Center, they are looking
> > > at the immunological aspects, i.e. what keeps most people from
> > > contracting the infection.
> > > > > My own pet theory, for which I have no proof whatsoever, is the
> > > changing perception of the contact lens as a consumer product rather
> > > than a medical device caused by a number of variables, and increasing
> > > emphasis on convenience. For some reason, it seems that more people
> > > consider it their right not to be inconvenienced. The end result?
> > > Less attention paid to lens hygeine.
> > > > > DrG
> > > We had plenty of doctors very interested in my daughter's case and one
> > doctor too stated it could possibly be a missing gene in their immune
> > system that protects others from this parasite. Allergies, possibly,
> > with medicines that cause the eye to be dryer, don't know. Our tears
> > do perform a protective barrier against most bacteria. I will email
> > you the Chicago and Philadelphia studies. The doctors in these two
> > cities are very concerned about this spike as well. I would like to
> > know how many cases of Acanthamoeba have occurred in Texas in the last
> > several years. I have read with interest about Dr. Niederkorn and his
> > studies on the immunity issue.
> I know Dr. Niederkorn, and we're practically neighbors.
> DrG

Small world. Would be interested to get his expert opinion on these
issues and to ascertain if there are increasing trends in Texas. My
guess is his expertise in this field already demonstrates there is a
heightened concern.

  #67  
Old 06-04-2006, 06:50 PM
Dr. Leukoma
Guest
 
Posts: n/a
Default Re: will acuvvue oasys or advance 2 be okay for swimming?


mb wrote:
- quote -

> Dr. Leukoma wrote:
> > mb wrote:
> > > > > Obviously, since this is such a virulent parasite as we cannot even
> > > develop effective antibiotics to kill this parasite, let alone put
> > > these cleaning agents in our contact lens solutions, all the more
> > > reason for warnings. I am fearful this Acanthamoeba trend will
> > > continue and we are entitled to find out why.
> > > I guess I need to see some statistics supporting this "trend." Or, is
> > it just a "spike" caused by temporary local environmental factors such
> > as warmer water, less rainfall causing lakes to be lower, etc. Here at
> > the University of Texas Southwestern Medical Center, they are looking
> > at the immunological aspects, i.e. what keeps most people from
> > contracting the infection.
> > > My own pet theory, for which I have no proof whatsoever, is the
> > changing perception of the contact lens as a consumer product rather
> > than a medical device caused by a number of variables, and increasing
> > emphasis on convenience. For some reason, it seems that more people
> > consider it their right not to be inconvenienced. The end result?
> > Less attention paid to lens hygeine.
> > > DrG
> We had plenty of doctors very interested in my daughter's case and one
> doctor too stated it could possibly be a missing gene in their immune
> system that protects others from this parasite. Allergies, possibly,
> with medicines that cause the eye to be dryer, don't know. Our tears
> do perform a protective barrier against most bacteria. I will email
> you the Chicago and Philadelphia studies. The doctors in these two
> cities are very concerned about this spike as well. I would like to
> know how many cases of Acanthamoeba have occurred in Texas in the last
> several years. I have read with interest about Dr. Niederkorn and his
> studies on the immunity issue.

I know Dr. Niederkorn, and we're practically neighbors.

DrG

  #66  
Old 06-04-2006, 05:21 PM
mb
Guest
 
Posts: n/a
Default Re: will acuvvue oasys or advance 2 be okay for swimming?


Dr. Leukoma wrote:
- quote -

> mb wrote:
> > > Obviously, since this is such a virulent parasite as we cannot even
> > develop effective antibiotics to kill this parasite, let alone put
> > these cleaning agents in our contact lens solutions, all the more
> > reason for warnings. I am fearful this Acanthamoeba trend will
> > continue and we are entitled to find out why.
> I guess I need to see some statistics supporting this "trend." Or, is
> it just a "spike" caused by temporary local environmental factors such
> as warmer water, less rainfall causing lakes to be lower, etc. Here at
> the University of Texas Southwestern Medical Center, they are looking
> at the immunological aspects, i.e. what keeps most people from
> contracting the infection.
> My own pet theory, for which I have no proof whatsoever, is the
> changing perception of the contact lens as a consumer product rather
> than a medical device caused by a number of variables, and increasing
> emphasis on convenience. For some reason, it seems that more people
> consider it their right not to be inconvenienced. The end result?
> Less attention paid to lens hygeine.
> DrG

We had plenty of doctors very interested in my daughter's case and one
doctor too stated it could possibly be a missing gene in their immune
system that protects others from this parasite. Allergies, possibly,
with medicines that cause the eye to be dryer, don't know. Our tears
do perform a protective barrier against most bacteria. I will email
you the Chicago and Philadelphia studies. The doctors in these two
cities are very concerned about this spike as well. I would like to
know how many cases of Acanthamoeba have occurred in Texas in the last
several years. I have read with interest about Dr. Niederkorn and his
studies on the immunity issue.

Absolutely on your pet theory. We have that proof, as the FDA 4 years
ago deregulated the plano contact lens as cosmetic, which was sold in
dollar stores, because it was a non-prescription lens. It took another
two years to get Congress to pass the Plano Contact Lens bill. I
emailed 100 senators in July 2005 about this issue and other appalling
facts that I discovered. Two days later that legislation was passed in
full and now is a law that all contact lenses are medical devices, not
to be sold without a prescription. Were they listening to me and my
anguished pleas for change? And do you believe there are now states
trying to overturn this legislation. Daniel Troy, acting
administrator, at that time, saw no problem with deregulating this
medical device. And who suffered the consequences - our youth, the
ultimate risktakers.

It is also an industry marketing their products as quick and
convenient. It is a very powerful industry regardless of what good
doctors recommend to their patients.

  #65  
Old 06-04-2006, 04:18 PM
Dr. Leukoma
Guest
 
Posts: n/a
Default Re: will acuvvue oasys or advance 2 be okay for swimming?


mb wrote:
- quote -

> Obviously, since this is such a virulent parasite as we cannot even
> develop effective antibiotics to kill this parasite, let alone put
> these cleaning agents in our contact lens solutions, all the more
> reason for warnings. I am fearful this Acanthamoeba trend will
> continue and we are entitled to find out why.

I guess I need to see some statistics supporting this "trend." Or, is
it just a "spike" caused by temporary local environmental factors such
as warmer water, less rainfall causing lakes to be lower, etc. Here at
the University of Texas Southwestern Medical Center, they are looking
at the immunological aspects, i.e. what keeps most people from
contracting the infection.

My own pet theory, for which I have no proof whatsoever, is the
changing perception of the contact lens as a consumer product rather
than a medical device caused by a number of variables, and increasing
emphasis on convenience. For some reason, it seems that more people
consider it their right not to be inconvenienced. The end result?
Less attention paid to lens hygeine.

DrG

  #64  
Old 06-04-2006, 02:45 PM
mb
Guest
 
Posts: n/a
Default Re: will acuvvue oasys or advance 2 be okay for swimming?


Dr. Leukoma wrote:
- quote -

> mb wrote:
> > Dr. Leukoma wrote:
> > > mb wrote:
> > > > > > > > > Yes, he is a renowned lasik surgeon. My daughter would let no one
> > > > touch her eye except him. His hands are gifted as well as his mind.
> > > > We could not have been under better care than that, facing the prospect
> > > > that she almost lost her eye battling this infection.
> > > > > Interestingly, I know what that is like first hand. One of my most
> > > recent patients was damaged by LASIK in 1998, performed by a very
> > > gifted surgeon. She hasn't let anyone touch her eyes until now.
> > > > > DrG
> > > My naivete must be showing. All of us common people put so much trust
> > in our doctors when they help us, but even gifted doctors make mistakes
> > or procedures just simply go wrong. Yes, lasik can be blindness as
> > well as better sight. You are right, of course, no one is protecting
> > the consumer on that front either. I am just not surprised anymore.
> > Our eyesight has been underprotected for years on all fronts.
> > Something needs to change.
> > > I hope your gifted hands can restore your patient's sight.
> She is quite happy. I just like to keep things in perspective. There
> is a jungle of misinformation out there.
> By the way, I have been told repeatedly by Alcon that their Optifree
> kills acanthamoeba cysts after 6 hours. I know that hydrogen peroxide
> kills the cysts as well after a 6 hour soak. This means a 6 hour soak
> in the full 3% strength. The unfortunate thing is that the leading
> hydrogen peroxide disinfection system begins to neutralize the hydrogen
> peroxide as soon as the contact lenses are put into the container. I
> am referring of course to the one with the grey disk at the bottom.
> It might interest you that at the time of the last "acanthamoeba scare"
> almost twenty years ago, there was no effective pharmaceutical agent
> against it initially.
> DrG

Yes, I need you experts to keep me in perspective as my passion on this
issue overcomes me sometimes. And I am glad there are good doctors
like you out there who truly care about their patients. We need you
and sometimes rely solely on your expertise.

Optifree Express is one of the solutions I would feel comfortable using
if I wore contacts, and they have validated that for you. Since some
solutions cannot even claim acanthamoebicidal, all the more reason for
"no swimming" and water related disclosures on all products as that
clearly puts you at risk; regardless of how low the risk, there is a
risk.

Sadly so, yes, you just lost your eye 15-20 years ago. Jackie's doctor
was involved in some of the original research during that epidemic that
was studied at the CDC while he was a Fellow at Emory University in
Atlanta, between 1984-86. He has been clearly aware and has treated
these infections for quite a long time.

Obviously, since this is such a virulent parasite as we cannot even
develop effective antibiotics to kill this parasite, let alone put
these cleaning agents in our contact lens solutions, all the more
reason for warnings. I am fearful this Acanthamoeba trend will
continue and we are entitled to find out why.

  #63  
Old 06-04-2006, 01:22 PM
Dr. Leukoma
Guest
 
Posts: n/a
Default Re: will acuvvue oasys or advance 2 be okay for swimming?


mb wrote:
- quote -

> Dr. Leukoma wrote:
> > mb wrote:
> > > > > > Yes, he is a renowned lasik surgeon. My daughter would let no one
> > > touch her eye except him. His hands are gifted as well as his mind.
> > > We could not have been under better care than that, facing the prospect
> > > that she almost lost her eye battling this infection.
> > > Interestingly, I know what that is like first hand. One of my most
> > recent patients was damaged by LASIK in 1998, performed by a very
> > gifted surgeon. She hasn't let anyone touch her eyes until now.
> > > DrG
> My naivete must be showing. All of us common people put so much trust
> in our doctors when they help us, but even gifted doctors make mistakes
> or procedures just simply go wrong. Yes, lasik can be blindness as
> well as better sight. You are right, of course, no one is protecting
> the consumer on that front either. I am just not surprised anymore.
> Our eyesight has been underprotected for years on all fronts.
> Something needs to change.
> I hope your gifted hands can restore your patient's sight.

She is quite happy. I just like to keep things in perspective. There
is a jungle of misinformation out there.

By the way, I have been told repeatedly by Alcon that their Optifree
kills acanthamoeba cysts after 6 hours. I know that hydrogen peroxide
kills the cysts as well after a 6 hour soak. This means a 6 hour soak
in the full 3% strength. The unfortunate thing is that the leading
hydrogen peroxide disinfection system begins to neutralize the hydrogen
peroxide as soon as the contact lenses are put into the container. I
am referring of course to the one with the grey disk at the bottom.

It might interest you that at the time of the last "acanthamoeba scare"
almost twenty years ago, there was no effective pharmaceutical agent
against it initially.

DrG

 

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